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dc.contributor.authorHüche Larsen, H.
dc.contributor.authorFrisk, R. F.
dc.contributor.authorWillerslev-Olsen, M.
dc.contributor.authorNielsen, J. B.
dc.date.accessioned2021-10-07T07:39:32Z
dc.date.available2021-10-07T07:39:32Z
dc.date.issued2021
dc.identifier.citationHüche Larsen, Helle et al. ‘Motor-learning Based Activities May Improve Functional Ability in Adults with Severe Cerebral Palsy: A Controlled Pilot Study’. 1 Jan. 2021 : 273 – 283.en_US
dc.identifier.urihttps://hdl.handle.net/11250/2788287
dc.description.abstractBACKGROUND: Cerebral palsy (CP) is a neurodevelopmental disturbance characterized by impaired control of movement. Function often decreases and 15% of adults are classified as severely affected (Gross Motor Function Classification Scale III-V). Little is known about interventions that aim to improve functional abilities in this population. OBJECTIVE: To evaluate a 12-week intervention based on motor learning principles on functional ability in adults with severe CP. METHODS: 16 adults (36±10 years, GMFCS III-V) were enrolled and divided into an intervention group (Active group) and a standard care group (Control group). Primary outcome measure was Gross Motor Function Measure (GMFM-88). Secondary measures were neurological status. The Active group were measured at baseline, after the intervention and at one-month follow-up. The Control group were measured at baseline and after one month. RESULTS: Analysis showed statistically significant improvement in GMFM-88 for the Active group from baseline to post assessment compared with the Control group (group difference: 5 points, SE 14.5, p = 0.008, CI: 1.2 to 8.7). Improvements were maintained at follow-up. Results from the neurological screening showed no clear tendencies. CONCLUSIONS: The study provides support that activities based on motor learning principles may improve gross motor function in adults with severe CP.en_US
dc.publisherNeuroRehabilitationen_US
dc.subjectmotor learningen_US
dc.subjectmotor functionen_US
dc.subjectneurorehabilitationen_US
dc.subjectrehabilitationen_US
dc.subjecttrainingen_US
dc.subjectneuroplasticityen_US
dc.subjectcerebral palsyen_US
dc.titleMotor-learning based activities may improve functional ability in adults with severe cerebral palsy: A controlled pilot studyen_US
dc.typeJournal articleen_US
dc.source.pagenumber273-283en_US
dc.source.volume48en_US
dc.source.journalNeuroRehabilitationen_US
dc.source.issue3en_US
dc.identifier.doihttps://doi.org/10.3233/nre-201581
dc.description.localcodemåsjekkes


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