dc.contributor.author | Johnell, Kristina | |
dc.contributor.author | Fastbom, Johan | |
dc.date.accessioned | 2017-06-07T12:40:56Z | |
dc.date.available | 2017-06-07T12:40:56Z | |
dc.date.issued | 2008 | |
dc.identifier.citation | Johnell, K. og Fastbom, J. (2008) Multi-dose drug dispensing and inappropriate drug use: a nationwide register-based study of over 700 000 elderly. Scandinavian Journal of Primary Health Care, 26(2), s. 86-91. | |
dc.identifier.uri | http://hdl.handle.net/11250/2445147 | |
dc.description | Tverrsnittstudie, kartlegging av hvorvidt bruk av multidose er forbundet med potensielt uhensiktsmessig legemiddelbruk. | |
dc.description.abstract | Objective: to investigate whether the use of multi-dose drug dispensing is associated with potentially inappropriate drug use (IDU). Design: Cross-sectional nationwide register-based study. Setting: Sweden. Subjects: people aged ]75 years registered in the Swedish Prescribed Drug Register during October December 2005. Main outcome measures: potentially IDU, i.e. anticholinergic drugs, long-acting benzodiazepines, concurrent use of three or more psychotropic drugs, and combinations of drugs that may lead to potentially serious drug drug interactions (DDIs). Results: after adjustment for age and number of dispensed drugs, any IDU, anticholinergic drugs, and three or more psychotropic drugs were associated with multi-dose drug dispensing, whereas the opposite relationship prevailed for long-acting benzodiazepines among women and potentially serious DDIs in both men and women. Among the subjects aged 75-79 years, multi-dose drug dispensing was even more strongly associated with any IDU, anticholinergic drugs, three or more psychotropic drugs in both men and women, and long-acting benzodiazepines among men. Conclusion: our results indicate that multi-dose users may be more exposed to potential IDU. However, multi-dose users seem to have a lower probability of potentially serious DDIs. Future research on multi-dose drug dispensing is necessary to ensure a high quality of drug therapy within this system. | |
dc.language.iso | eng | |
dc.subject | pasientsikkerhet | |
dc.subject | legemiddel | |
dc.subject | legemiddelbruk | |
dc.subject | multidose | |
dc.subject | legemiddelhåndtering | |
dc.subject | legemiddelforskrivning | |
dc.subject | uhensiktsmessig legemiddelbruk | |
dc.subject | tverrsnittstudie | |
dc.subject | allmennmedisin | |
dc.subject | allmennpraksis | |
dc.subject | eldre | |
dc.subject | Sverige | |
dc.title | Multi-dose drug dispensing and inappropriate drug use: a nationwide register-based study of over 700 000 elderly | |
dc.type | Journal article | |
dc.type | Peer reviewed | |
dc.rights.holder | Johnell, Kristina | |
dc.source.volume | 26 | |
dc.source.journal | Scandinavian Journal of Primary Health Care | |
dc.source.issue | 2 | |
dc.identifier.doi | 10.1080/02813430802022196 | |